Is glaucoma, in fact, diabetes of the brain?

Researchers at All India Institute of Medical Sciences and Ambedkar Centre for Biomedical Research India have proposed a new mechanism of glaucoma which suggests that diabetes can occur in the brain and may be the cause of many neurodegenerative disorders including glaucoma. Glaucoma is the leading cause irreversibly blinding disorders and affects millions worldwide. There is no known cure to glaucoma. The disease is considered as one of the most complex human diseases. Muneeb Faiq and his coworkers have attempted to explain this disorder which may open door for a new era of research on this disease.

Glaucoma is an irreversibly blinding disorder with almost 65 million sufferers worldwide. There is no cure for glaucoma and the best that can be done is lowering of the intraocular pressure pharmacologically and/or surgically. However many patients continue to progress to blindness despite an apparently controlled or low intraocular pressure. Proper understanding about the underlying etiopathogenic and mechanistic aspects of glaucoma is necessary to develop therapeutic regimens and management strategies of this disorder. The recent paper titled "Glaucoma: Diabetes of the brain - a radical hypothesis about its nature and pathogenesis", published in Medical Hypotheses, is a thorough scientific insight into what might be the actual facets and underlying molecular secrets of this disease.

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